Lymph Node

,

Sentinel Lymph Node Biopsy May Predict Prognosis in Extramammary Paget Disease

,
Sentinel Lymph Node Biopsy May Predict Prognosis in Extramammary Paget Disease

Routine sentinel lymph node biopsy (SLNB) may help predict prognosis in patients with extramammary Paget disease (EMPD) of the genital area without clinical lymph node enlargement, according to study results published in the Journal of Dermatology.

Researchers sought to determine whether clinical characteristics and biomarkers before primary tumor resection could predict the invasion level of primary tumors and sentinel lymph node (SLN) metastasis in patients with EMPD. They retrospectively reviewed the data of patients who had primary tumor resection and SLNB for EMPD in the genital region from August 2002 to December 2024 at a single center.

,

The role of sentinel lymph node biopsy in the management of invasive extramammary Paget's disease: Multi-center, retrospective study of 151 patients

,
The role of sentinel lymph node biopsy in the management of invasive extramammary Paget's disease: Multi-center, retrospective study of 151 patients

We collected 151 patients with invasive extramammary Paget's disease. The rate of LN metastasis in patients without lymphadenopathy was 15%. On the other hand, patients with lymphadenopathy had LN metastasis in 80%. No difference in survival between patients with or without SLN metastasis. Patients with lymphadenopathy showed worse survival than those with positive SLN.

© myEMPD.com • Helping those with extramammary Paget’s disease (EMPD).